Cell and molecular biology

Heads or tails? Polarized notum activation at wounds inhibits Wnt function to promote planarian head regeneration

Annotated by Melissa McCartney PhD

Annotated on 03/13/2012

Originally published 05/13/2011

A new diagnostic strategy for prostate cancer Urine TMPRSS2:ERG fusion transcript stratifies prostate cancer risk in men with elevated serum PSA

Annotated by Johanna Sandlund

Annotated on 07/10/2013

Originally published 08/03/2011

What the pelvis can teach us about evolution Adaptive evolution of pelvic reduction in sticklebacks by recurrent deletion of a Pitx1 enhancer

Annotated by Gillian R. Siegal

Annotated on 07/24/2013

Originally published 12/10/2009

The art of DNA DNA origami with complex curvatures in three-dimensional space

Annotated by John A. Means

Annotated on 12/04/2013

Originally published 04/15/2011

Cracking the armor Crocodile head scales are not developmental units but emerge from physical cracking

Annotated by Desiree Stanley

Annotated on 06/02/2014

Originally published 11/29/2012

Jumping genes! Dosage compensation via transposable element mediated rewiring of a regulatory network

Annotated by Parmit Singh

Annotated on 10/10/2014

Originally published 11/15/2013

Lights, motor neurons, and muscle action! Optical control of muscle function by transplantation of stem cell-derived motor neurons in mice

Annotated by Polly Huang

Annotated on 01/09/2015

Originally published 04/04/2014

One RING to fool them all: Shedding light on BRCA1 mutations BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity

Annotated by Adam Thomas

Annotated on 02/06/2015

Originally published 10/28/2011

Fussy about filaments Actin network architecture can determine myosin motor activity

Annotated by Samantha Knoll

Annotated on 01/23/2015

Originally published 06/08/2012

Budding yeast cells turn back the clock Gametogenesis eliminates age-induced cellular damage and resets life span in yeast

Annotated by Brett Robison

Annotated on 02/20/2015

Originally published 06/24/2011

Overcrowding in neuronal synapses Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

Annotated by Ihab Boulas, Catherine Eisenhaur, Shazzad Hossain Mukit …

Annotated on 04/03/2015

Originally published 05/30/2014

Take more naps, become more attractive A critical period of sleep for development of courtship circuitry and behavior in drosophila

Annotated by Emily Mason

Annotated on 04/17/2015

Originally published 04/18/2014

Shape shifters of the plant world Leaf shape evolution through duplication, regulatory didversification, and loss of a homeobox gene

Annotated by Greg Crowther

Annotated on 05/15/2015

Originally published 02/14/2014

Stop! Codon time! Stop codon reassignments in the wild

Annotated by Parmit Singh

Annotated on 06/12/2015

Originally published 05/23/2014

A shoot full of sugar helps the flowering begin Regulation of flowering by trehalose-6-phosphate signaling in Arabidopsis thaliana

Annotated by Greg Crowther, Courtney Abrams, Shuvam Chaudhari …

Annotated on 07/24/2015

Originally published 02/08/2013

Cells mix things up by actively stirring their insides High-resolution mapping of intracellular fluctuations using carbon nanotubes

Annotated by Wylie Ahmed

Annotated on 08/07/2015

Originally published 05/30/2014

It's not easy being green tomatoes Uniform ripening encodes a Golden 2-like transcription factor regulating tomato fuit chloroplast development

Annotated by Cristina Walcher-Chevillet

Annotated on 09/04/2015

Originally published 06/29/2012

Mosquitoes be gone Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection

Annotated by John Huang

Annotated on 09/18/2015

Originally published 05/23/2014

An eft of a central newt from (Notophthalmus viridescens louisianensis) Iowa. / Physon, CC

Limb regeneration: Fact or (science) fiction? Molecular basis for the nerve dependence of limb regeneration in an adult vertebrate

Annotated by Jason Librande

Annotated on 07/29/2016

Originally published 11/02/2007

Does smoking make a man less of a man? Smoking is associated with mosaic loss of chromosome Y

Annotated by Robin Williamson

Annotated on 12/11/2015

Originally published 01/02/2015

Mimicking a bundle of waste: Influenza A virus strategic attack Influenza A virus uses the aggresome processing machinery for host cell entry

Annotated by Jole Fiorito

Annotated on 01/22/2016

Originally published 10/24/2014

Getting to know your neighbors: Parasitic plants traffic RNA with their hosts Genomic-scale exchange of mRNA between a parasitic plant and its hosts

Annotated by Yana V. Miteva

Annotated on 03/04/2016

Originally published 08/15/2014

Does bad luck cause cancer? Variation in cancer risk among tissues can be explained by the number of stem cell divisions

Annotated by Alyssa Chamberlain

Annotated on 04/29/2016

Originally published 01/02/2015

Inflammation: The first responders need help Neutrophils scan for activated platelets to initiate inflammation

Annotated by Archana Gopalakrishnan

Annotated on 06/23/2016

Originally published 12/05/2014

A golden fish reveals pigmentation loss in Europeans SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans

Annotated by Brett Robison, Sandra Blumenrath

Annotated on 05/20/2016

Originally published 12/16/2005

Arrested development: When cells make mistakes Requirement for p53 and p21 to sustain G2 arrest after DNA damage

Annotated by Adam Thomas

Annotated on 06/17/2016

Originally published 11/20/1998

Origin of immunity Fate mapping analysis reveals that adult microglia derive from primitive macrophages

Annotated by Tatiana Schnieder

Annotated on 07/18/2016

Originally published 11/05/2010

The building blocks of Alzheimer's Reducing endogenous tau ameliorates amyloid ß-induced deficits in an Alzheimer's disease mouse model

Annotated by Hilary Gerstein

Annotated on 10/07/2016

Originally published 05/04/2007